Resilience in methamphetamine use disorder: A cross-sectional study on the role of childhood trauma, aggression, and temperament.

Stress plays a crucial role in the development and course of substance use disorders, including methamphetamine use disorder (MAUD). Psychological resilience refers to one's ability to cope with stress and adversity. In many psychiatric disorders, resilience is related to many factors such as impulsivity, aggression, childhood trauma, and affective temperament. However, these associations have been poorly studied in MAUD. This study aimed to explore key factors associated with resilience in individuals with MAUD. In total, 114 patients with MAUD were recruited. All participants completed the resilience scale for adults (RSA), Beck depression inventory (BDI), Barratt impulsiveness scale, 11th version (BIS-11), Buss-Perry Aggression Questionnaire (AQ), Childhood Trauma Questionnaire (CTQ), and Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Auto-Questionnaire version (TEMPS-A). Linear regression analysis was used to determine the factors associated with resilience. There was no significant correlation between resilience and daily amount or duration of methamphetamine use. The total scores for depression, aggression, impulsivity, childhood emotional neglect, emotional abuse, and childhood physical abuse were negatively correlated with resilience scores. Childhood emotional abuse and emotional neglect, anger, and depressive and hyperthymic temperaments significantly predicted resilience (Adjusted R2 = 0.354). Interventions to enhance resilience that consider temperament traits, aggression, and a history of childhood trauma may make important contributions to the treatment of individuals with MAUD.