Management of a High-Beta-Human Chorionic Gonadotropin (β-HCG) Ectopic Pregnancy With Methotrexate: A Case Report.

Ectopic pregnancy is a severe complication of early pregnancy that can lead to significant morbidity and mortality. Methotrexate is a standard non-surgical treatment for ectopic pregnancy, especially in cases where beta-human chorionic gonadotropin (β-HCG) levels are low. However, its effectiveness decreases as β-HCG levels rise. We present a case of a 38-year-old nulliparous woman with a high-β-HCG level ectopic pregnancy, who was managed successfully with methotrexate despite initial concerns about potential treatment failure. This case underscores the importance of patient-centered care, thorough counseling, and a multidisciplinary approach in managing complex ectopic pregnancies, particularly when standard guidelines may not fully apply. The patient was closely monitored and achieved a successful outcome without the need for surgery.