Ophthalmology · 1999
Association of high-dose intravenous methylprednisolone with reversal of blindness from lightning in two patients.
Клинический случайСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Norman M E, Younge B R
Аннотация
OBJECTIVE: To report possibly beneficial effects of treatment with high-dose corticosteroids given intravenously to two patients with loss of vision after lightning strikes.
DESIGN: Case reports.
PARTICIPANTS: Two patients who suffered the effects of a lightning strike.
INTERVENTION: High-dose intravenous methylprednisolone (NASCIS-2 Protocol).
MAIN OUTCOME MEASURES: Vision recovery, pupil responses, and optic nerve appearance.
RESULTS: One patient had unilateral ophthalmoscopically visible abnormality with light perception vision and a relative afferent defect in that eye; vision recovered to 20/25. The other patient had no light perception, nonreactive pupils, and normal fundus examinations in both eyes; vision recovered bilaterally to normal (20/20).
CONCLUSIONS: High-dose intravenous corticosteroid treatment in these patients may have had a role in their visual recovery.
DESIGN: Case reports.
PARTICIPANTS: Two patients who suffered the effects of a lightning strike.
INTERVENTION: High-dose intravenous methylprednisolone (NASCIS-2 Protocol).
MAIN OUTCOME MEASURES: Vision recovery, pupil responses, and optic nerve appearance.
RESULTS: One patient had unilateral ophthalmoscopically visible abnormality with light perception vision and a relative afferent defect in that eye; vision recovered to 20/25. The other patient had no light perception, nonreactive pupils, and normal fundus examinations in both eyes; vision recovered bilaterally to normal (20/20).
CONCLUSIONS: High-dose intravenous corticosteroid treatment in these patients may have had a role in their visual recovery.