Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025
Management of indolent mastocytosis and mast cell activation syndrome: A clinical yardstick.
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Akin Cem, Butterfield Joseph H, Castells Mariana, Lyons Jonathan J
Аннотация
Knowledge and understanding of mast cell biology and mast cell disorders have increased in the past several years, with new classifications of diseases for both clonal and nonclonal forms. Along with these classifications has come differing treatment paradigms, including novel therapies now approved for various forms of clonal mast cell disorders. Unfortunately, there is some lack of guidance on how best to use these therapies. This yardstick aims to provide the clinician with a review of available therapies to treat mast cell activation syndrome and indolent systemic mastocytosis and an evidence-based expert opinion approach regarding on how best to use these therapies.