ALL Figured Out? Primary Leukemic Pulmonary Infiltration in an Adolescent with Acute Lymphoblastic Leukemia: A Case Report and a Brief Review of the Literature.

Leukemic infiltration of the lungs is rarely reported in children. Clinical symptoms are often variable and nonspecific, making diagnosis challenging. The actual frequency of pulmonary involvement, the severity of local findings, and typical imaging characteristics in pediatric patients remain largely unclear. Most literature studies on the radiological features of leukemic lung infiltration have focused on adults, leaving a significant gap in pediatric data. This lack of information can hinder clinical and radiological assessment in children. Here, we present a case of leukemic pulmonary infiltration in an adolescent with nonspecific symptoms and markedly abnormal computed tomographic findings. We describe the morphological abnormalities, discuss differential diagnoses, and review the limited literature on pulmonary involvement in childhood leukemia. Further studies are needed to better characterize the frequency, types, and imaging features of leukemic pulmonary infiltration in children.