Convulsive Seizure as a Presenting Symptom of Extreme Anaemia: A Case Report.

Extreme anaemia (haemoglobin <2g/dL) is rarely encountered, and the clinical manifestation of this entity remains unclear. A woman in her 60s who enjoyed good past health presented with a two-week history of generalized malaise and then a sudden onset of convulsive seizure. Blood tests revealed haemoglobin of 1.7g/dL with acute kidney injury and elevated liver enzymes and creatine kinase. She was subsequently diagnosed with myelodysplastic syndrome with erythroid hypoplasia. After receiving a supportive blood transfusion, she had significant improvement in both clinical and biochemical parameters. Our case illustrates that extreme anaemia can present with seizure and multiple organ dysfunction secondary to tissue ischaemia.