Linezolid and Meropenem for Nocardia otitidiscaviarum Actinomycetoma, India.

Treatment of actinomycotic mycetoma with joint involvement is challenging. We present a patient in India with actinomycotic mycetoma who reached complete cure and remission after linezolid and meropenem treatment with a 2-year posttreatment follow-up. Clinicians should use novel drug regimens based on subspecies variations of Nocardia and regional drug susceptibility patterns to guide therapy.