Expression of Concern on "Myo-inositol, D-chiro-inositol, folic acid and manganese in second trimester of pregnancy: a preliminary investigation".

The Editor in Chief and the Publisher are issuing an expression of concern regarding the following article: Malvasi A, Casciaro F, Minervini MM, Kosmas I, Mynbaev OA, Pacella E, Monti Condesnitt V, Creanza A, Di Renzo GC, Tinelli A. Myo-inositol, D-chiro-inositol, folic acid and manganese in second trimester of pregnancy: a preliminary investigation. Eur Rev Med Pharmacol Sci. 2014;18(2):270-4. PMID: 24488919. Post-publication concerns have been raised regarding the reliability of certain data and analyses reported in this article. The authors informed the journal that the original data underlying the study are no longer available, as the article was published 12 years ago. An independent assessment identified concerns related to aspects of the statistical analysis and highlighted limitations in verifying the robustness and reproducibility of the reported findings based on the information currently available in the published article. As the journal has been unable to independently verify the reliability of the data and analyses, the Editor in Chief and the Publisher are issuing this Expression of Concern to ensure that readers are aware of these unresolved issues. Readers are advised to interpret the findings of this article with caution. The Publisher apologizes for any inconvenience this may cause.