Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases · 2000
[Changes in T-lymphocyte subsets of peripheral blood in patients with filarial chyluria].
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Gu X T, Gao Z G, Shen B R, Hu G Z, Tang X L, Ma Q
Аннотация
OBJECTIVE: To study the changes in T-lymphocyte subsets CD4+:CD8+ of peripheral blood in 29 patients with present chyluria(PPC), 29 patients with chyluria history but without chyluria (PNPC) and 38 healthy controls.
METHODS: The determination of CD3+, CD4+ and CD8+ was conducted using test reagents kits.
RESULTS: The percentage of CD3+, CD4+ cell were signfcantly decreased in PPS group than in PNPC and healthy control group, the ratio of CD4+/CD8+ being under 1.0. The T-lymphocyte subsets (CD3+, CD4+, CD8+) and CD4+/CD8+ ratio of both PNPC and healthy control group were all within normal range.
CONCLUSION: The immune function of the patients with filarial chyluria was impaired in terms of the changes in T-lymphocyte subsets.
METHODS: The determination of CD3+, CD4+ and CD8+ was conducted using test reagents kits.
RESULTS: The percentage of CD3+, CD4+ cell were signfcantly decreased in PPS group than in PNPC and healthy control group, the ratio of CD4+/CD8+ being under 1.0. The T-lymphocyte subsets (CD3+, CD4+, CD8+) and CD4+/CD8+ ratio of both PNPC and healthy control group were all within normal range.
CONCLUSION: The immune function of the patients with filarial chyluria was impaired in terms of the changes in T-lymphocyte subsets.