[Changes in T-lymphocyte subsets of peripheral blood in patients with filarial chyluria].

OBJECTIVE

To study the changes in T-lymphocyte subsets CD4+:CD8+ of peripheral blood in 29 patients with present chyluria(PPC), 29 patients with chyluria history but without chyluria (PNPC) and 38 healthy controls.

METHODS

The determination of CD3+, CD4+ and CD8+ was conducted using test reagents kits.

RESULTS

The percentage of CD3+, CD4+ cell were signfcantly decreased in PPS group than in PNPC and healthy control group, the ratio of CD4+/CD8+ being under 1.0. The T-lymphocyte subsets (CD3+, CD4+, CD8+) and CD4+/CD8+ ratio of both PNPC and healthy control group were all within normal range.

CONCLUSION

The immune function of the patients with filarial chyluria was impaired in terms of the changes in T-lymphocyte subsets.