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DOI 10.12688/wellcomeopenres.23909.2

Медицинская библиотека · Wellcome open research · 2025

Impact of Heat on Birth Outcomes and Child Nutrition: Study Protocol using the CIDACS Birth Cohort.

Ribeiro-Silva Rita de Cássia, Pepper Maxine, Ribas de Farias Costa Priscila, Rodrigues Cortes Taisa, Sacramento Lais, Ribeiro Lais Helena, Passos Luz Lisianne, Ranzani Otavio T, Smeeth Liam, Brickley Elizabeth B, Dos Santos Rocha Aline, M Pescarini Julia, Falcão Ila, Rebouças Poliana, Delgado Danielson, Silveira Ismael, S Paixão Enny, Barreto Mauricio

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Аннотация

BACKGROUND

Pregnant individuals and children are particularly vulnerable to the adverse health consequences of exposure to heat. Leveraging the robust ecosystem of Brazilian linked administrative data, we aim to advance our understanding of how high temperatures and heatwaves influence birth outcomes and child nutrition.

OBJECTIVES

Investigate the association between high ambient temperatures/ heatwaves and 1) birth outcomes (low birth weight (LBW), small for gestational age (SGA), large for gestational age (LGA), and preterm birth), 2) child nutrition (growth), and 3) breastfeeding practices and complementary feeding in children.

METHODS

We will triangulate results from complementary analytical approaches, including time-stratified case-crossover designs and time-to-event techniques. We will explore the influence of high temperatures and heatwaves at different periods (or lags) preceding the event and apply distributed lag non-linear models to account for delayed and non-linear effects. We will conduct subgroup analyses to identify the population groups most at risk.

RESULTS AND

CONCLUSIONS

Our study will generate new insights into the relationship between heat, birth outcomes, and child nutrition in Brazil. By providing evidence from a middle-income country with diverse ecosystems and climate zones in a context of social inequalities, this research will contribute to advancing the current knowledge base. Additionally, by identifying critical windows of vulnerability and at-risk groups, our findings can potentially inform targeted and equitable climate adaptation policies.

Для цитирования: Ribeiro-Silva Rita de Cássia, Pepper Maxine, Ribas de Farias Costa Priscila, Rodrigues Cortes Taisa, Sacramento Lais, Ribeiro Lais Helena, Passos Luz Lisianne, Ranzani Otavio T, Smeeth Liam, Brickley Elizabeth B, Dos Santos Rocha Aline, M Pescarini Julia, Falcão Ila, Rebouças Poliana, Delgado Danielson, Silveira Ismael, S Paixão Enny, Barreto Mauricio. Impact of Heat on Birth Outcomes and Child Nutrition: Study Protocol using the CIDACS Birth Cohort.. Wellcome open research. 2025. DOI: 10.12688/wellcomeopenres.23909.2.
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