Toxicology reports · 2026
Intoxication with nutmeg: A case presentation and analysis of Swiss poisons information center (Tox Info Suisse) enquiries 2014-2023.
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Bleisch Amadea, Späni Selina, Schumann Regina, Dongre Kanchan, Degrandi Colette, Leuppi-Taegtmeyer Anne
Аннотация
INTRODUCTION: Nutmeg is a widely used culinary spice. When ingested in large quantities it has psychoactive and hallucinogenic effects.
CASE REPORTS: We present the case of a 23-year-old man on long-term fluoxetine and quetiapine who ingested 75 g of nutmeg with suicidal intent. Four hours later, he presented himself to the emergency department of the nearest hospital with tachycardia and mydriasis. He was transferred to the intensive care unit of Cantonal Hospital Baselland for further monitoring where, approximately 14 h after ingestion, he became somnolent. All symptoms resolved spontaneously within 26 h.We also analyzed enquiries to the Swiss national poison information center (Tox Info Suisse) about possible nutmeg intoxication from 2014 to 2023. During this period, enquiries for 236 patients were made (51% female, 0 - 85 years old). The largest number of enquiries (N = 30) occurred during 2020 and 2021, coinciding with a TikTok nutmeg challenge and an increase in the popularity of home baking during the COVID-19 pandemic.
DISCUSSION: Nutmeg is a widely available household spice with ingredients that can cause toxic effects when ingested in large quantities. Intoxications usually show a mild course, as in the case we describe here, despite long term medication with fluoxetine. The analysis of enquires to Tox Info Suisse suggest that the incidence of enquiries about possible nutmeg intoxication might be subject to social influences.
CASE REPORTS: We present the case of a 23-year-old man on long-term fluoxetine and quetiapine who ingested 75 g of nutmeg with suicidal intent. Four hours later, he presented himself to the emergency department of the nearest hospital with tachycardia and mydriasis. He was transferred to the intensive care unit of Cantonal Hospital Baselland for further monitoring where, approximately 14 h after ingestion, he became somnolent. All symptoms resolved spontaneously within 26 h.We also analyzed enquiries to the Swiss national poison information center (Tox Info Suisse) about possible nutmeg intoxication from 2014 to 2023. During this period, enquiries for 236 patients were made (51% female, 0 - 85 years old). The largest number of enquiries (N = 30) occurred during 2020 and 2021, coinciding with a TikTok nutmeg challenge and an increase in the popularity of home baking during the COVID-19 pandemic.
DISCUSSION: Nutmeg is a widely available household spice with ingredients that can cause toxic effects when ingested in large quantities. Intoxications usually show a mild course, as in the case we describe here, despite long term medication with fluoxetine. The analysis of enquires to Tox Info Suisse suggest that the incidence of enquiries about possible nutmeg intoxication might be subject to social influences.