Fertility treatment use and breastfeeding outcomes.

BACKGROUND

About 15% of women aged 15-44 years in the United States experience infertility. Factors associated with infertility and fertility treatments may also be associated with lactation difficulties. Limited data exist examining the impact of infertility or mode of conception on breastfeeding outcomes.

OBJECTIVE

The objectives of this study were to report breastfeeding outcomes (initiation and duration at 8 weeks) among women who conceived spontaneously compared to women who conceived using fertility treatments (assisted reproductive technology [ART], intrauterine insemination, or fertility-enhancing drugs).

MATERIALS AND

METHODS

Maternal-reported data from 4 states from the 2012-2015 Pregnancy Risk Assessment and Monitoring System (PRAMS) were used to explore use of fertility treatment and breastfeeding initiation and continuation at 8 weeks (n = 15,615). Data were weighted to represent all women delivering live births within each state; SAS survey procedures were used to account for PRAMS complex survey design. Stepwise, multivariable logistic regression, adjusted for maternal demographics, parity, plurality, mode of delivery, preterm birth, and maternal pre-pregnancy health conditions, was used to quantify the associations between fertility treatment use and breastfeeding.

RESULTS

Mode of conception was not associated with breastfeeding outcomes when comparing women who conceived spontaneously to women who conceived using any fertility treatment. The odds of breastfeeding at 8 weeks were lower among women who conceived using ART, after adjusting for basic demographic covariates (adjusted odds ratio [aOR], 0.71; 95% confidence interval [CI], 0.52-0.97) and additionally adjusting for maternal health conditions (aOR, 0.68; 95% CI, 0.49-0.93), but this difference was no longer significant after adjusting for plurality and preterm birth (aOR, 0.74; 95% CI, 0.54-1.02).

CONCLUSION

This study suggests that mothers who conceive using ART may breastfeed for shorter durations than mothers who conceive spontaneously, partially mediated by an increased likelihood of multiples and infants born preterm. Studies are needed to elucidate these associations and to understand the intentions and barriers to breastfeeding among women who conceive with the help of ART.