Anticancer research · 2019
Diameter of External Carotid Arteries in Patients With Mandibular Osteoradionecrosis.
СтатьяНазвание и аннотация: Перевод в очереди
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Ishibashi Naoya, Maebayashi Toshiya, Aizawa Takuya, Sakaguchi Masakuni, Okada Masahiro
Аннотация
BACKGROUND/AIM: To evaluate the association between osteoradionecrosis (ORN) of the mandible and stenosis of the external carotid artery after radiation therapy (RT) for head and neck cancer.
PATIENTS AND METHODS: The computed tomography images of 42 patients (36 men, six women; median age, 64.5 years) treated with RT for head and neck cancer between January 2011 and December 2015 were reviewed. The cross-sectional diameters of the bilateral external carotid arteries were measured on contrast-enhanced images taken after completion of RT.
RESULTS: Nine of the 42 included patients (21.4%) developed ORN after a median interval of 34 months from completion of RT. Univariate analysis revealed that external carotid artery diameter ≤ the median diameter was significantly associated with ORN development (p=0.008 and 0.013). In multivariate analysis, left external carotid artery diameter ≤ the median was significantly associated with ORN development (p=0.023).
CONCLUSION: External carotid artery stenosis was significantly associated with ORN development.
PATIENTS AND METHODS: The computed tomography images of 42 patients (36 men, six women; median age, 64.5 years) treated with RT for head and neck cancer between January 2011 and December 2015 were reviewed. The cross-sectional diameters of the bilateral external carotid arteries were measured on contrast-enhanced images taken after completion of RT.
RESULTS: Nine of the 42 included patients (21.4%) developed ORN after a median interval of 34 months from completion of RT. Univariate analysis revealed that external carotid artery diameter ≤ the median diameter was significantly associated with ORN development (p=0.008 and 0.013). In multivariate analysis, left external carotid artery diameter ≤ the median was significantly associated with ORN development (p=0.023).
CONCLUSION: External carotid artery stenosis was significantly associated with ORN development.