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Aging · 2024

Molecular subgroup establishment and signature creation of lncRNAs associated with acetylation in lung adenocarcinoma.

СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Chen Hao, Wang Yuanyong, Shao Changjian, Guo Kai, Liu Guanglin, Wang Zhaoyang, Duan Hongtao, Pan Minghong, Ding Peng, Zhang Yimeng, Han Jing, Yan Xiaolong

Аннотация

BACKGROUND: Emergency medical services (EMS) system characteristics that promote quality pediatric care are uncertain. We evaluated agency and patient demographic factors associated with improved performance.

METHODS: We evaluated care for children (aged <18 years) with a ground scene-level response using the 2020-2023 National EMS Information System (NEMSIS) datasets. We identified outcomes based on the NEMSIS Prehospital Pediatric Quality Measures Dashboard, including beta agonist for asthma/wheezing; glucagon/glucose for hypoglycemia; epinephrine for anaphylaxis; intravenous fluids for hypotension; pain improvement in trauma; pain assessment in trauma; and vital sign documentation in trauma. We evaluated the association of agency- and patient-level factors with high performance on each performance measure using mixed-effects logistic models.

RESULTS: We identified 2 739 756 encounters. The proportion of cases achieving the performance measure ranged from 22.5% (improvement in pain for children with trauma reporting pain) to 85.2% (documentation of vital signs for children with trauma). Older age was associated with higher performance for most measures. Black and Hispanic and Latino children with trauma were less likely to have an improvement in pain compared with white children (adjusted odds ratio [aOR], 0.84 and 0.89, respectively) but were more likely to receive epinephrine for anaphylaxis (aOR, 1.50 and 1.32, respectively). There was improved performance over time for 4 measures. Most agency-level factors were not consistently associated with quality of care.

CONCLUSION: EMS pediatric care quality is associated with multiple patient factors, including age. Further research is needed to determine whether these associations impact patient outcomes and to develop strategies to reduce unwarranted variability in prehospital pediatric care.

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