Macrocephaly Secondary to Superior Vena Cava Syndrome.

Cardiac defects in neonates are often associated with neurological or neuroanatomical anomalies. We present a patient who developed macrocephaly secondary to superior vena cava syndrome, resultant from repair of her congenital tetralogy of Fallot. She was managed conservatively with serial imaging and close observation from the neurosurgical aspect, and her head growth stabilized without requiring ventriculoperitoneal shunting after stent placement in her superior vena cava. In patients with macrocephaly secondary to cardiac issues, cerebrospinal fluid diversion is often performed quickly. For our patient - who had no obvious signs of worsening intracranial hypertension or symptoms beyond macrocephaly - treatment of her overall cardiovascular issues was successful in achieving stability of her head circumference growth.