Outcomes of transcatheter patent ductus arteriosus closure in infants weighing 2 to 6 kg.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Malekzadeh-Milani Sophie, Padovani Paul, Sivakumar Kothandam, Goronflot Thomas, Méot Mathilde, Jones Matthew I, Lwin Naychi, Ovaert Caroline, Hascoët Sébastien, Jalal Zakaria, Bautista-Rodriguez Carles, Gewillig Marc, Lucron Hugues, Averin Konstantin, Kahl Béatrice Susanne, Gudnason Janus Freyr, Torres Alejandro J, Lefort Bruno, Saliba Zakhia, Houeijeh Ali, Galeczka Michal, Samion Hasri, El Saiedi Sonia, Lange Juan Manuel, Yaakobi-Simhayoff Nurit, Callegari Alessia, Christensen Anders Haugom, Ystgaard Martin B, Selly Jean-Bernard, Bouvaist Hélène, Neil Deborah, Sirico Domenico, Karsenty Clément, Vargas-Acevedo Catalina, Mejia Ernesto, Rosenthal Eric, Grunenwald Céline, Benbrik Nadir, Werner Oscar, Chauvire-Drouard Anne, Gloanec Marine, Moktadir Antoine, Thambo Jean-Benoit, Brard Mélanie, Laforest Gérald, Sagar Pramod, Joseph Anu, Puthiyedath Thejaswi, Holmstrom Henrik, Fiszer Roland, Wåhlander Håkan, Michel-Behnke Ina, Bonnet Damien, Gourraud Pierre-Antoine, Butera Gianfranco, Qureshi Shakeel A, Fraisse Alain, Morgan Gareth J, Baruteau Alban-Elouen
Аннотация
METHODS: An international, multicenter, retrospective cohort study was conducted in 31 tertiary hospitals in 17 countries between 2000 and 2023, investigating all infants who underwent attempted transcatheter PDA closure with a procedural weight of 2-to-6kg.
RESULTS: Attempted transcatheter PDA closure was performed in 1231 infants (median [Q1-Q3] weight, 4747 [3700-5300] g; median age, 132 [83-194] days; ex-preterm, n=581 [56.8%]) with a 95.0% success rate. A composite outcome of procedural failure or major adverse events was observed in 173 (14%) patients, including device embolization in 64 (3.7%), device-induced left pulmonary artery stenosis in 47 (2.7%), and procedural death in 2 (0.2%). Logistic regression model analysis identified a 2- to 3.9-kg procedural weight, increased pulmonary artery pressure, and window-type or tubular ductal morphologies as independent predictors of the composite outcome. Based on propensity score matching analysis, 2- to 3.9-kg infants had a risk ratio of 2.19 (95%CI, 1.25-3.83) for experiencing the composite outcome, compared with 4- to 5.9-kg infants.
CONCLUSIONS: Transcatheter PDA closure in 2- to 6-kg infants was feasible in most patients. Procedural failure or major adverse events occurred in 14% and several independent risk factors were identified, including the 2- to 3.9-kg weight range identified as a higher-risk subgroup. These findings may improve risk stratification and the decision-making process.