The Journal of the American Association of Gynecologic Laparoscopists · 2002
The potential of preoperative beta-hCG and progesterone levels to predict failure of laparoscopic linear salpingostomy in ectopic pregnancies.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Tews Gernot, Ebner Thomas, Yaman Cemil, Pölz Werner, Sommergruber Michael, Hartl Johannes
Аннотация
STUDY OBJECTIVE: To estimate the association between preoperative beta-human chorionic gonadotropin (hCG) and progesterone levels, and success of linear salpingostomy in treatment of tubal pregnancy.
DESIGN: Retrospective case control study (Canadian Task Force classification II-1).
SETTING: Women's general hospital.
PATIENTS: Three hundred five women undergoing laparoscopic linear salpingostomy for ectopic pregnancy.
INTERVENTION: Examination of risk factors for surgical failure of salpingostomy by analyzing corresponding receiver operating curves.
MEASUREMENTS AND MAIN RESULTS: In 305 women, intervention was successful in 272 and failed in 33, as assessed by either postoperative hemorrhage (16) or rising beta-hCG values (14); 3 women had both. Of 295 patients in whom beta-hCG was evaluated preoperatively, 149 (50.5%) had values of 1000 mU/ml. or less; 75% had progesterone levels of 10 ng/ml or below. No association was found between preoperative beta-hCG and progesterone levels and the success of linear salpingostomy.
CONCLUSION: Preoperative beta-hCG and progesterone levels are of no significance with regard to success of linear salpingostomy for treatment of tubal pregnancy.
DESIGN: Retrospective case control study (Canadian Task Force classification II-1).
SETTING: Women's general hospital.
PATIENTS: Three hundred five women undergoing laparoscopic linear salpingostomy for ectopic pregnancy.
INTERVENTION: Examination of risk factors for surgical failure of salpingostomy by analyzing corresponding receiver operating curves.
MEASUREMENTS AND MAIN RESULTS: In 305 women, intervention was successful in 272 and failed in 33, as assessed by either postoperative hemorrhage (16) or rising beta-hCG values (14); 3 women had both. Of 295 patients in whom beta-hCG was evaluated preoperatively, 149 (50.5%) had values of 1000 mU/ml. or less; 75% had progesterone levels of 10 ng/ml or below. No association was found between preoperative beta-hCG and progesterone levels and the success of linear salpingostomy.
CONCLUSION: Preoperative beta-hCG and progesterone levels are of no significance with regard to success of linear salpingostomy for treatment of tubal pregnancy.
Предметные рубрики MeSH
AdultBiomarkersCase-Control StudiesChorionic Gonadotropin, beta Subunit, HumanConfidence IntervalsFemaleFollow-Up StudiesHumansPredictive Value of TestsPregnancyPregnancy, EctopicPreoperative CareProbabilityProgesteroneROC CurveRetrospective StudiesSalpingostomySensitivity and SpecificityTreatment Outcome