Reconstruction of large defect of lower lip and commissure using Karapandzic flap: case report.

Xeroderma Pigmentosum (XP) is a photosensitive skin disease with a high risk for developing skin malignancy. We present an 18-years-old boy with XP and recurrent basal and squamous cell carcinoma of lower lip. Because of scars from earlier resections Karapandzic circumoral advancement-rotation flap was performed. The method is suitable for defects covering 1/3 to 4/5 of the lower lip with possible involvement of commisura. 70% of the lip was resected and reconstruction was made with bilateral flaps. This reconstruction resulted in good oral muscular and sensory function. The scars followed natural folds of the face and despite a slight microstomia gave an acceptable esthetic appearance. The Karapandzic flap is simple and safe method for reconstruction of large defects of lower lip.