The monster of Ascheraden: A description of syndromic cryptophthalmos by poet Daniel Hermann in "De monstroso partu…" published in Riga, 1596.

In 1596, the Niclas Mollyn (Nicolaus Mollinus; 1550/55-1625) printing house in Riga, published a book in Latin, authored by Prussian poet and humanist Daniel Hermann (1543-1601) with quite an intriguing title "De monstroso partu…" or "About the monstrous birth: on August 18 of the year 1595 in the district of Ascheraden on the other side of the Duna in Livonia and on things that happen against the laws of nature. An ethical, natural and historical discourse." The "Monstroso partu…" is among the earliest books printed in Riga and the first one dedicated to a medical topic. The book contains what could be seen as the earliest known description of syndromic cryptophthalmos aka Fraser syndrome.