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DOI 10.1093/ajcn/nqy369

Медицинская библиотека · The American journal of clinical nutrition · 2019

Habitual coffee consumption and risk of falls in 2 European cohorts of older adults.

Machado-Fragua Marcos D, Struijk Ellen A, Ballesteros Juan-Manuel, Ortolá Rosario, Rodriguez-Artalejo Fernando, Lopez-Garcia Esther

СтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

BACKGROUND

Habitual coffee consumption has been associated with lower risk of type 2 diabetes, cardiovascular disease, and sarcopenia, which are strong risk factors of falls. In addition, caffeine intake stimulates attention and vigilance, and reduces reaction time. Therefore, a protective effect of coffee on the risk of falling can be hypothesized.

OBJECTIVES

The aim of this study was to examine the association between habitual coffee consumption and the risk of ≥1 falls, injurious falls, and falls with fracture in older people.

METHODS

Data were taken from 2964 participants aged ≥60 y from the Seniors-ENRICA (Study on Nutrition and Cardiovascular Risk in Spain) cohort and 8999 participants aged ≥60 y from the UK Biobank cohort. In the Seniors-ENRICA study, habitual coffee consumption was assessed with a validated diet history in 2008-2010, and falls were ascertained up to 2015. In the UK Biobank study, coffee was measured with 3-5 multiple-pass 24-h food records starting in 2006, and falls were assessed up to 2016.

RESULTS

A total of 793 individuals in Seniors-ENRICA and 199 in UK Biobank experienced ≥1 fall during follow-up. After multivariable adjustment for major lifestyle and dietary risk factors and compared with daily consumption of <1 cup of coffee, the pooled HR for ≥1 fall was 0.75 (95% CI: 0.52, 1.07) for total coffee consumption of 1 cup/d and 0.74 (95% CI: 0.62, 0.90) for ≥2 cups/d (P-trend = 0.001). The corresponding figures for caffeinated coffee were 0.67 (95% CI: 0.42, 1.07) and 0.70 (95% CI: 0.56, 0.87) (P-trend < 0.001). Decaffeinated coffee was not associated with risk of falling in the analyzed cohorts. In Seniors-ENRICA, there was a tendency to lower risk of injurious falls among those consuming caffeinated coffee (HR: 0.83; 95% CI: 0.68, 1.00 for 1 cup/d; HR: 0.83; 95% CI: 0.64, 1.09 for ≥2 cups/d; P-trend = 0.09). No association was observed between caffeinated or decaffeinated coffee consumption and risk of falls with fracture.

CONCLUSIONS

Habitual coffee consumption was associated with lower risk of falling in older adults in Spain and the United Kingdom.

Для цитирования: Machado-Fragua Marcos D, Struijk Ellen A, Ballesteros Juan-Manuel, Ortolá Rosario, Rodriguez-Artalejo Fernando, Lopez-Garcia Esther. Habitual coffee consumption and risk of falls in 2 European cohorts of older adults.. The American journal of clinical nutrition. 2019. DOI: 10.1093/ajcn/nqy369.

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