BMC anesthesiology · 2026
Feasibility of remimazolam rescue sedation for neonatal MRI: a case report.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Wu Di, Chen Lin, Cheng Jing, Yue Cheng Jing, Quan Yingyao
Аннотация
BACKGROUND: High-quality neonatal imaging often necessitates sedation or anesthesia to minimize motion artifacts. However, procedural sedation for non-painful pediatric examinations outside the operating room presents unique challenges due to their distinct cardiopulmonary physiology and drug metabolism. Although remimazolam is associated with minimal hemodynamic and respiratory effects in adults, evidence supporting its use in neonatal MRI remains limited.
CASE DESCRIPTION: We report the first successful application of remimazolam for MRI sedation in an early-term neonate (37 ⁴⁄₇ weeks' gestational age, 2.9 kg). After unsuccessful non-pharmacologic measures and intranasal dexmedetomidine, intravenous remimazolam (0.1 mg/kg) produced adequate sedation within 1 min, allowing completion of a 17-minute MRI examination while preserving hemodynamic and respiratory stability.
CONCLUSIONS: This case highlights potential utility of remimazolam s a rescue sedative for neonatal MRI sedation. Comprehensive multicenter studies are warranted to evaluate its safety, efficacy, and role in clinical practice.
CASE DESCRIPTION: We report the first successful application of remimazolam for MRI sedation in an early-term neonate (37 ⁴⁄₇ weeks' gestational age, 2.9 kg). After unsuccessful non-pharmacologic measures and intranasal dexmedetomidine, intravenous remimazolam (0.1 mg/kg) produced adequate sedation within 1 min, allowing completion of a 17-minute MRI examination while preserving hemodynamic and respiratory stability.
CONCLUSIONS: This case highlights potential utility of remimazolam s a rescue sedative for neonatal MRI sedation. Comprehensive multicenter studies are warranted to evaluate its safety, efficacy, and role in clinical practice.