Frontiers in oncology · 2026
Effect of a nurse-led multidisciplinary team model on chemotherapy-induced nausea and vomiting in lung cancer patients.
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Liu Wei, Peng Qian, Gan Xiuni
Аннотация
OBJECTIVE: To explore the effect of a nurse-led multidisciplinary team (MDT) model on chemotherapy-induced nausea and vomiting (CINV) in lung cancer patients.
METHODS: A total of 126 non-small cell lung cancer patients undergoing platinum-based chemotherapy were divided into a control group (routine care, n=63) and an experimental group (nurse-led MDT intervention, n=63). The primary outcome was the incidence of grade ≥II CINV. Secondary outcomes included scores on the Functional Living Index-Emesis (FLIE), patient cognition of CINV, and satisfaction with CINV management.
RESULTS: The experimental group showed significantly lower frequency and severity of nausea and vomiting at day 5 of chemotherapy cycle 2 (P<0.05). FLIE scores, patient cognition, and satisfaction were all significantly higher in the experimental group (all P<0.001). No severe adverse events were reported during follow-up.
CONCLUSION: The nurse-led MDT model effectively reduces the severity of CINV, improves quality of life and patient satisfaction, and enhances the standardized management of CINV.
METHODS: A total of 126 non-small cell lung cancer patients undergoing platinum-based chemotherapy were divided into a control group (routine care, n=63) and an experimental group (nurse-led MDT intervention, n=63). The primary outcome was the incidence of grade ≥II CINV. Secondary outcomes included scores on the Functional Living Index-Emesis (FLIE), patient cognition of CINV, and satisfaction with CINV management.
RESULTS: The experimental group showed significantly lower frequency and severity of nausea and vomiting at day 5 of chemotherapy cycle 2 (P<0.05). FLIE scores, patient cognition, and satisfaction were all significantly higher in the experimental group (all P<0.001). No severe adverse events were reported during follow-up.
CONCLUSION: The nurse-led MDT model effectively reduces the severity of CINV, improves quality of life and patient satisfaction, and enhances the standardized management of CINV.