The International journal of pharmacy practice · 2026
A study of micro-dosing-transferring from methadone to buprenorphine in NHS Dumfries & Galloway.
СтатьяНазвание и аннотация: Перевод в очереди
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Nairn Samantha, Steele Sean, Bell Eilish, Blount Mark
Аннотация
OBJECTIVES: To find a novel way to successfully transition patients from methadone to buprenorphine and in turn reduce the percentage of methadone prescribed within National Health Service Dumfries & Galloway (NHS D&G).
METHODS: Three micro-dosing schedules were developed. Outcomes measured: patient numbers, success rates, prior methadone dose, Opiate Substitution Therapy following micro-dosing. A patient feedback questionnaire was developed.
KEY FINDINGS: 177 patients micro-dosed between 06/09/21 and 28/05/24. Around 132 patients successfully transitioned from methadone to buprenorphine through micro-dosing (74.5%). Shift in prescribing: 60.5% buprenorphine/39.5% methadone.
CONCLUSION: Micro-dosing is now a standardized approach to transitioning from methadone to buprenorphine in NHS Dumfries & Galloway.
METHODS: Three micro-dosing schedules were developed. Outcomes measured: patient numbers, success rates, prior methadone dose, Opiate Substitution Therapy following micro-dosing. A patient feedback questionnaire was developed.
KEY FINDINGS: 177 patients micro-dosed between 06/09/21 and 28/05/24. Around 132 patients successfully transitioned from methadone to buprenorphine through micro-dosing (74.5%). Shift in prescribing: 60.5% buprenorphine/39.5% methadone.
CONCLUSION: Micro-dosing is now a standardized approach to transitioning from methadone to buprenorphine in NHS Dumfries & Galloway.