Медицинская библиотека · Infection · 2001

Nocardial brain abscess: observation of treatment strategies and outcome in Switzerland from 1992 to 1999.

Loeffler J M, Bodmer T, Zimmerli W, Leib S L

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Аннотация

BACKGROUND

Brain abscesses caused by Nocardia spp. are rare, but life-threatening infections that are notoriously difficult to diagnose and treat and which occur mainly in immunocompromised patients. Standard treatment guidelines are not available.

METHODS

A systematic search for nocardial brain abscesses from 1992 to 1999 was conducted in Switzerland for the comparison of clinical presentation, treatment strategies and outcome.

RESULTS

Seven cases were found, for which data of six were available. In 4/6 patients antimicrobial therapy led to a decrease in the size of abscesses. Four of six patients died. The cause of death was likely due to underlying co-morbidities, rather than the nocardial infection.

CONCLUSION

The finding that treatment was different in each case underscores the lack of therapeutic guidelines.

Для цитирования: Loeffler J M, Bodmer T, Zimmerli W, Leib S L. Nocardial brain abscess: observation of treatment strategies and outcome in Switzerland from 1992 to 1999.. Infection. 2001. DOI: 10.1007/s15010-001-1147-1.

Предметные рубрики MeSH

Adult Aged Anti-Bacterial Agents Brain Abscess Drug Therapy, Combination Female Humans Immunocompromised Host Male Middle Aged Neurosurgical Procedures Nocardia Nocardia Infections Practice Guidelines as Topic Retrospective Studies Switzerland Treatment Outcome

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