Evaluation of a laser-based sensor for the diagnosis of neurological disorders.

Involuntary muscle activities like fasciculations or tremor are an indication for several neurological disorders. However, currently used techniques for measuring those activities are limited due to their invasiveness, the unsuitability for measuring a whole body simultaneously and the lack of an objective measurement of amplitude and duration of muscle activity. Hence, we developed a new laser-based sensor for the remote quantification of muscle activity. In the present paper we show a basic evaluation of our system by reference to ultrasound measurements. Our results show the detection limits of our remote sensor technology in terms of fasciculation size and depth within the muscle. Those results will help us for a better interpretation of our measurement results and hold promise for the future development of our system.