Feasibility and Safety of Percutaneous Device Closure of Patent Ductus Arteriosus in Preterm Neonates: Experience From a Single Center in Northern India.

OBJECTIVE

To report the feasibility and safety of percutaneous device closure of patent ductus arteriosus (PDA) in preterm neonates from a tertiary center in Northern India.

METHODS

A retrospective chart review of the clinical profile, nature of device used, and outcomes of inborn preterm neonates who underwent percutaneous device closure of PDA was conducted. The intervention was performed by experienced pediatric cardiologists using a transvenous approach under fluoroscopic guidance.

RESULTS

Ten neonates with median (Q1, Q3) gestation of 29 (27, 30) weeks underwent device (Piccolo device) closure at a median (Q1, Q3) age of 37 (27, 41) days. At the time of procedure, the median (Q1, Q3) weight of the infants was 1270 (1120, 1890) g and the median (Q1, Q3) PDA diameter was 3.0 (2.3, 3.0) mm. Successful PDA closure was achieved in nine neonates; six showed clinical improvement. No procedure-related death was observed.

CONCLUSIONS

Percutaneous device closure of PDA in preterm neonates is safe and feasible.