International journal of pediatric otorhinolaryngology · 2021
Ear reconstruction research using animal models: The effect of fat grafting on costal cartilage stents.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Chen Xia, Zhang Ruhong, Li Datao, Zhang Qun, Xu Zhicheng, Xu Feng, Li Yiyuan, Li Tianya
Аннотация
OBJECT: For congenital microtia patients with a depressed mastoid area, it is unclear whether autologous fat grafting to fill the depressed area of the cheek will affect the survival of the subsequent grafted costal cartilage stent. An animal model was used for in vivo research to provide guidance for clinical applications.
METHODS: Autologous costal cartilage was implanted in nude mice. Fat samples were collected at different time points and histological examination performed to analyze the activity of chondrocytes and the deposition of the chondrocyte matrix.
RESULTS: This nude mouse fat transplantation model study showed that there were statistical differences in chondrocyte viability between the fat filling group and the control group, but there was no statistical difference in the effect on collagen content.
CONCLUSION: Transplanting fat reduces the viability of chondrocytes, but has little effect on collagen matrix deposition.
METHODS: Autologous costal cartilage was implanted in nude mice. Fat samples were collected at different time points and histological examination performed to analyze the activity of chondrocytes and the deposition of the chondrocyte matrix.
RESULTS: This nude mouse fat transplantation model study showed that there were statistical differences in chondrocyte viability between the fat filling group and the control group, but there was no statistical difference in the effect on collagen content.
CONCLUSION: Transplanting fat reduces the viability of chondrocytes, but has little effect on collagen matrix deposition.