[The prevalence of Chlamydia trachomatis and Ureaplasma urealyticum cervical infection in infertility women and the observation of therapeutic efficacy].

OBJECTIVE

To study the prevalence of Chlamydia trachomatis (CT) and Ureaplasma urealyticum (Uu) cervical infection in infertility women, and therapeutic effectiveness of tetracycline and qianglimycin.

METHOD: CT in cervical swab specimen was detected by cell culture, polymerase chain reaction(PCR) and immunofluorescent assay(IFA), Uu in cervical swab specimen was detected by culture, in a group of 145 infertility women, before and after treatment, and 45 women at productive age who attended obstetric and gynecologic clinic.

RESULT: The positive rate of CT by cell culture, PCR, IFA(shell) and IFA(direct smear) was 62.7%, 66.8%, 64.8% and 36.5%, respectively, which was obviously higher than that of the control (P < 0.01). The positive rate of Uu was 33.1%, that of CT and Uu co-infection was 18.6%. Both were obviously higher than those of the control (P < 0.01).

CONCLUSION

This study indicates that the prevalence of CT and Uu cervical infection in infertility women is high. CT and Uu cervical infection is closely related to female infertility. The therapeutic effectiveness of tetracycline and qianglimycin is not ideal.