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DOI 10.1172/jci136564

Медицинская библиотека · The Journal of clinical investigation · 2020

MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons.

Abreu Ana Paula, Toro Carlos A, Song Yong Bhum, Navarro Victor M, Bosch Martha A, Eren Aysegul, Liang Joy N, Carroll Rona S, Latronico Ana Claudia, Rønnekleiv Oline K, Aylwin Carlos F, Lomniczi Alejandro, Ojeda Sergio, Kaiser Ursula B

СтатьяПоддержка NIH: внешняя программаПеревод пока не подготовлен

Аннотация

INTRODUCTION

The ureter is present in surgical field during inguinal hernia repair in 0.5-4% of cases. It typically occurs in obese patients, in men and patients after kidney transplants. Right-sided and indirect location of ureteral herniation prevails. The clinical picture is mostly asymptomatic, but possible manifestations include increased frequency of urination with urgency, nocturia, recurrent pyelonephritis, urosepsis, feeling of incomplete emptying of the bladder, signs of GIT obstruction. Diagnostic methods include retrograde pyelography or CT urography. Surgical treatment is indicated in every case of ureteral herniation. Reposition of the ureter retroperitoneally and standard plasty of the inguinal canal is the method of choice.

METHODS

33 cases of ureteral hernia were reviewed in order to write a systematized review of the topic. The case report describes a 68-year-old patient with prostatic hyperplasia and dysuria treated at our institution. A preoperative CT examination with intravenous contrast showed herniation of the right ureter into the inguinal area with hydronephrosis of 2nd degree. Preoperative insertion of a mono-J stent into the right ureter and reposition of the ureter retroperitoneally followed by hernia repair using alloplastic material was performed. There were no postoperative complications.

RESULTS AND

CONCLUSION

In risky cases, the surgeon should assume the possible presence of a ureter in the inguinal region. Careful dissection in the inguinal area reduces the risk of iatrogenic damage to the ureter.

Для цитирования: Abreu Ana Paula, Toro Carlos A, Song Yong Bhum, Navarro Victor M, Bosch Martha A, Eren Aysegul, Liang Joy N, Carroll Rona S, Latronico Ana Claudia, Rønnekleiv Oline K, Aylwin Carlos F, Lomniczi Alejandro, Ojeda Sergio, Kaiser Ursula B. MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons.. The Journal of clinical investigation. 2020. DOI: 10.1172/jci136564.

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