A serological survey of antibodies to Streptomyces somaliensis and Actinomadura madurae in the Sudan enzyme linked immunosorbent assay (ELISA).

Sera from 160 individuals resident in the Gezira, and 40 living in Khartoum, Sudan, were screened for antibodies to Streptomyces somaliensis and Actinomadura madurae using enzyme linked immunosorbent assay (ELISA). Antibodies were detected in 11.2% of those from the Gezira (6.8% to S. somaliensis, 4.3% to A. madurae, and 0.6% to both) compared to 2.5% of those resident in Khartoum. The ratio of men with antibodies compared to women was about 2:1 in those from Gezira. The results encouraged further epidemiological surveys are mycetoma in Sudan using ELISA.