[The role of determining specific pregnancy proteins in the diagnosis of progressing tubal pregnancy].

The importance was studied of measurement of certain specific pregnancy proteins (b1-glycoproteid, SP-1, PAPP-A, PP-5) for the diagnosis of advancing fallopian pregnancy. The data secured suggest a statistically significant decrease in SP-1 and PAPP-A concentration in tubal implantation of a fetal egg as compared to uterine pregnancy. Changes in blood serum concentration of PP-5 in women with different variants of the fetal egg implantation were statistically insignificant, which fact suggests that measurement of the quantitative indices of the pregnant women blood serum SP-1 and PAPP-A may be regarded as an investigational method of sufficient information value to be used in detection and differential diagnosis of progressive pregnancy in a timely fashion.