Pneumologia (Bucharest, Romania) · 2010
[Bronchiolitis and pulmonary hypertension].
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Bardi-Peti Luiza, Ciofu Eugen Pascal
Аннотация
OBJECTIVES: The study was undertaken to assess whether previously healthy infants with bronchiolitis develop elevated pulmonary artery pressures.
MATERIAL AND METHODS: We performed 2D and Doppler echocardiography in 94 infants, aged between 2 and 12 months, from November 2007 to December 2009. 47 infants had bronchiolitis and 47 were in the control group. We excluded children with congenital heart diseases and other conditions associated with pulmonary hypertension. The method of time to peak velocity corrected for heart rate was used to estimate pulmonary arterial pressure (PAP). A Student's t-test for independent samples was used to compare the mean values of variables.
OUTCOMES: Increased mean pulmonary pressures (> 25 mmHg) were measured in 13 infants with bronchiolitis. The values were categorized as mild-moderate pulmonary hypertension. Mean PAP were significantly increased in subjects with bronchiolitis, vs. control (p = 0.001). In infants with bronchiolitis, hospitalisation was significantly longer at patients with pulmonary hypertension vs. normal PAP (p = 0.006). Mean PAP were significantly increased in subjects with a moderate/severe episode of wheezing at admission vs. a mild episode (p = 0.001).
CONCLUSION: Echocardiography brings valuable informations regarding pulmonary hypertension in bronchiolitis. PHT could be a criterion in establishing the severity of disease, a prognosis factor and an element of therapeutic guidance.
MATERIAL AND METHODS: We performed 2D and Doppler echocardiography in 94 infants, aged between 2 and 12 months, from November 2007 to December 2009. 47 infants had bronchiolitis and 47 were in the control group. We excluded children with congenital heart diseases and other conditions associated with pulmonary hypertension. The method of time to peak velocity corrected for heart rate was used to estimate pulmonary arterial pressure (PAP). A Student's t-test for independent samples was used to compare the mean values of variables.
OUTCOMES: Increased mean pulmonary pressures (> 25 mmHg) were measured in 13 infants with bronchiolitis. The values were categorized as mild-moderate pulmonary hypertension. Mean PAP were significantly increased in subjects with bronchiolitis, vs. control (p = 0.001). In infants with bronchiolitis, hospitalisation was significantly longer at patients with pulmonary hypertension vs. normal PAP (p = 0.006). Mean PAP were significantly increased in subjects with a moderate/severe episode of wheezing at admission vs. a mild episode (p = 0.001).
CONCLUSION: Echocardiography brings valuable informations regarding pulmonary hypertension in bronchiolitis. PHT could be a criterion in establishing the severity of disease, a prognosis factor and an element of therapeutic guidance.