Dental materials : official publication of the Academy of Dental Materials · 2026
Mechanical and biological properties of two new commercial PEEK framework materials for fixed and removable dental prostheses compared to unfilled PEEK: An in vitro study.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод в очереди
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Yassine Jamila, Mahmoud Barwin, Schmidt Franziska, Beuer Florian, Akhmad Rafik, Mao Zhen, Müller Wolf-Dieter, Schwitalla Andreas Dominik
Аннотация
OBJECTIVES: The aim of the study was to characterize a novel commercially available PEEK compound reinforced with inorganic fillers for fixed implant-supported dentures in two different shades (beige: Compound B; red: Compound R).
METHODS: Compound blanks were milled into standardized specimens and polished. Surface characteristics were assessed via contact profilometry (Ra), water contact angle (WCA), and Vickers microhardness at three force levels (HV1, HV0.5, HV0.2). Particle morphology and size distribution were analyzed through scanning electron microscopy and quantified using Fiji software. Flexural properties were evaluated via 3-point bending tests using small bars (1 mm × 2 mm × 15 mm), and compressive properties were determined using cylindrical samples (4 mm × 8 mm). Biocompatibility was evaluated according to ISO 10993-5 using immortalized human gingival fibroblasts (iHGF) and mouse calvaria pre-osteoblasts (MC3T3-E1) through CCK-8 and live/dead fluorescence assays to confirm the absence of cytotoxic effects.
RESULTS: Both compounds exhibited excellent polishability (Ra < 0.1 µm) and hydrophobic surface characteristics (WCA ∼80°). Compound R displayed significantly higher flexural strength (194.64 ± 15.44 MPa) and at the same time significantly lower flexural modulus (3.97 ± 0.45 GPa) than Compound B (172.6 ± 12.22 MPa and 4.3 ± 0.41 GPa respectively). Both compounds showed comparable compressive strengths and compressive moduli (171.01 ± 3.54 MPa (Compound B) and 172.3 ± 2.45 MPa (Compound R) and 5.53 ± 0.75 GPa (Compound B) and 5.96 ± 0.22 GPa (Compound R), respectively). Both compounds showed no cytotoxic effects in cell culture, demonstrating biocompatibility comparable to unfilled PEEK.
SIGNIFICANCE: The investigated PEEK materials demonstrated superior stiffness without compromising flexural strength, outperforming unfilled PEEK and conventional fiber-reinforced PEEK in terms of polishability and esthetics with comparable biocompatibility to unfilled PEEK. The findings suggest that the compounds could represent viable alternative prosthetic framework materials for fixed implant-supported restorations.
METHODS: Compound blanks were milled into standardized specimens and polished. Surface characteristics were assessed via contact profilometry (Ra), water contact angle (WCA), and Vickers microhardness at three force levels (HV1, HV0.5, HV0.2). Particle morphology and size distribution were analyzed through scanning electron microscopy and quantified using Fiji software. Flexural properties were evaluated via 3-point bending tests using small bars (1 mm × 2 mm × 15 mm), and compressive properties were determined using cylindrical samples (4 mm × 8 mm). Biocompatibility was evaluated according to ISO 10993-5 using immortalized human gingival fibroblasts (iHGF) and mouse calvaria pre-osteoblasts (MC3T3-E1) through CCK-8 and live/dead fluorescence assays to confirm the absence of cytotoxic effects.
RESULTS: Both compounds exhibited excellent polishability (Ra < 0.1 µm) and hydrophobic surface characteristics (WCA ∼80°). Compound R displayed significantly higher flexural strength (194.64 ± 15.44 MPa) and at the same time significantly lower flexural modulus (3.97 ± 0.45 GPa) than Compound B (172.6 ± 12.22 MPa and 4.3 ± 0.41 GPa respectively). Both compounds showed comparable compressive strengths and compressive moduli (171.01 ± 3.54 MPa (Compound B) and 172.3 ± 2.45 MPa (Compound R) and 5.53 ± 0.75 GPa (Compound B) and 5.96 ± 0.22 GPa (Compound R), respectively). Both compounds showed no cytotoxic effects in cell culture, demonstrating biocompatibility comparable to unfilled PEEK.
SIGNIFICANCE: The investigated PEEK materials demonstrated superior stiffness without compromising flexural strength, outperforming unfilled PEEK and conventional fiber-reinforced PEEK in terms of polishability and esthetics with comparable biocompatibility to unfilled PEEK. The findings suggest that the compounds could represent viable alternative prosthetic framework materials for fixed implant-supported restorations.
Предметные рубрики MeSH
AnimalsHumansMiceBenzophenonesBiocompatible MaterialsCell SurvivalCompressive StrengthDental MaterialsDental Prosthesis, Implant-SupportedDenture, Partial, FixedFibroblastsFlexural StrengthHardnessKetonesMaterials TestingMicroscopy, Electron, ScanningOsteoblastsParticle SizePolyether CompoundsPolyethylene GlycolsPolymersSurface Properties3T3 Cells