International journal of radiation biology · 2019
The BioDoseNet image repository used as a training tool for the dicentric assay.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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García Omar, Rada-Tarifa Ana, Lafuente-Álvarez Erika, González-Mesa Jorge E, Mandina Tania, Muñoz-Velastegui Gabriela, Astudillo-Silva Yanara, Monjagata Norma, Aguilar-Coronel Sara, de Vargas Aida Falcón
Аннотация
Purpose: This paper describes how the BioDoseNet image repository was used as a training tool for the dicentric assay.Materials and methods: The training was implemented in three phases: introduction to dicentric scoring, dose response curve elaboration and dose assessment exercise. Four labs without previous experience in the dicentric assay participated and four modules of the repository were used.Results: The labs become familiar with aberrations induced by ionizing radiation. The labs were able to generate data for the elaboration of a dose response curve and then successfully estimated doses and irradiated fractions in six blind samples.Conclusions: The performance of these laboratories during the exercise demonstrates the efficacy of the BioDoseNet image repository as a training tool and the utility of web based scoring for the dicentric assay community.