Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
Severe Vasoplegic Syndrome Treated with Angiotensin II and Hemoadsorption Therapy after Cardiac Surgery.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Lucchelli Matteo, Andreis Davide Tommaso, Gomarasca Mattia, Mistraletti Giovanni
Аннотация
Vasoplegic syndrome (VS) is a common complication after cardiac surgery with cardiopulmonary bypass (CPB). The main pathophysiology mechanism of VS includes a systemic inflammatory response syndrome due to surgical trauma, release of pro-inflammatory mediators caused by blood contact with foreign surfaces of heart-lung machine (pump and tubing) and endothelial dysfunction due to loss of pulsatile flow. Preoperative use of angiotensin-converting enzyme inhibitors and beta-blockers, coronary surgery and longer duration of CPB increase the incidence of VS. VS is characterized by hypotension with high cardiac output and low systemic resistance; treatment includes fluid resuscitation and vasopressors. Current authors report a case of cardiac VS, unresponsive to conventional therapy and successfully treated with angiotensin II (ATII) and hemoadsorption therapy.