Cross-Sectional Study of the PREValence of Erectile DysfunctIon in the Arteriopathic Population (PREVEDI).

BACKGROUND

Although the association between erectile dysfunction (ED) and cardiovascular disease is well established, its prevalence in patients with atherosclerosis remains poorly defined.

OBJECTIVES

To evaluate ED prevalence, severity, and associated risk factors (RFs) in patients with atherosclerotic disease.

MATERIALS AND

METHODS

This single-centre, cross-sectional, non-randomised observational study included male patients referred to a vascular surgery service with documented atherosclerotic disease. Erectile function was assessed using the International Index of Erectile Function-15 questionnaire, and RFs were analysed using univariable and multivariable regression models.

RESULTS

A total of 162 patients were enrolled (mean age, 70.1 ± 8.6 years); ED was present in 93.8%, with severe ED observed in 62.3%. Multivariable analysis confirmed age as a significant RF for ED, particularly > 75 years, while age, diabetes mellitus, and subjective ED duration were significantly associated with greater severity.

DISCUSSION: The high prevalence of ED supports its role as a manifestation of systemic vascular disease linked to endothelial dysfunction and diffuse atherosclerosis.

CONCLUSION

ED is highly prevalent among patients with clinically overt atherosclerotic disease requiring vascular surgery referral, and may represent a marker of systemic vascular pathology. Routine assessment of sexual function may improve cardiovascular risk stratification and preventive management.