Early body representation EEG signals in cervical vs. thoracic spinal cord injuries with neuropathic pain.

Spinal cord injury (SCI) not only causes severe sensorimotor impairments but also leads to disruptions in body representation, including body schema. While the neurological differences between cervical and thoracic injuries are well established, the impact of the level of injury on body schema is less understood. Deeper insights into how change in body schema is affected by injury severity may further individual rehabilitation strategies and outcomes for individuals with SCI. This study explores event-related potentials (ERPs) between individuals with cervical and thoracic injuries in response to body-related and non-body-related stimuli presented in two rotation angles (easy: 75° and difficult: 150°) while completing a laterality judgment task. Individuals with cervical injury showed reduced amplitudes of posterior P100 and anterior N100 compared to the thoracic group only when the body-related stimuli were presented in a difficult rotation angle. We discuss that the variations in early modulation of ERPs can be attributed to the underlying sensorimotor challenges associated with different levels of injury. This work enhances our understanding of cognitive processing in SCI populations to better inform rehabilitation strategies.