Primary Bone Tumors: Osteosarcoma and Ewing Sarcoma.

Substantial recent progress has been made in the management of osteosarcoma and Ewing sarcoma, the most common childhood bone sarcomas. Surgical treatment continues to evolve through navigation, 3D printing, biomaterials, and custom-growing implants. New targeted therapies on the horizon have the potential to achieve a breakthrough improvement in survivorship. Newer radiation modalities, such as proton and carbon-ion radiotherapy, have greater therapeutic potential than conventional photon-beam radiotherapy. This article provides a comprehensive review of common childhood sarcomas and highlights recent advances.