Exploring the Role of Post-Viral Phenomenon in the Pathogenesis of Achalasia: Insights From a Clinical Case.

Viral infections have been associated with the development of achalasia. A 43-year-old woman presented with 2 weeks of dysphagia. Medical history was notable for oral herpes, shingles, and recent COVID-19 infection. Her physical examination was unremarkable. A barium esophagram suggested esophageal dysmotility. Her symptoms did not respond to botulinum toxin injections and dilation of the esophagus. Achalasia type II was diagnosed via high-resolution esophageal manometry, and peroral endoscopic myotomy was performed with resolution of her symptoms. This case adds to the literature and highlights the need to further explore the pathophysiological link between viruses and achalasia.