Clinical and experimental obstetrics & gynecology · 2016
Evaluation of sialic acid levels in patients with hydatidiform mole: a preliminary study.
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Özcan H C, Öztürk E, Sucu S, Uğur M G, Kutlar I, Balat O, Erbağci B
Аннотация
PURPOSE OF INVESTIGATION: This study aims to investigate whether hydatidiform mole (HM) disease with malignant potential is significantly associated with increased sialic acid (SA) levels.
MATERIALS AND METHODS: A total of 114 women were enrolled in this study. Patients were divided into three groups including HM (Group 1, n = 34), control group including non-pregnant healthy patients (Group 2, n = 42), and another control group including healthy pregnant patients within 12 weeks of gestation (Group 3, n = 38). Serum-free SA levels were measured.
RESULTS: There was a statistically significant difference in serum-free SA levels among the groups (p ≤ 0.001). Patients with HM had significantly higher levels compared to the control groups.
CONCLUSION: The present study results showed that there was a significant correlation between HM and serum SA level.
MATERIALS AND METHODS: A total of 114 women were enrolled in this study. Patients were divided into three groups including HM (Group 1, n = 34), control group including non-pregnant healthy patients (Group 2, n = 42), and another control group including healthy pregnant patients within 12 weeks of gestation (Group 3, n = 38). Serum-free SA levels were measured.
RESULTS: There was a statistically significant difference in serum-free SA levels among the groups (p ≤ 0.001). Patients with HM had significantly higher levels compared to the control groups.
CONCLUSION: The present study results showed that there was a significant correlation between HM and serum SA level.