Biophysical testing in premature rupture of the membranes.

The management of pregnancies complicated by premature rupture of the membranes (PROM) should include some type of surveillance for the development of infectious complications. This is a necessity because neonatal sepsis is not heralded by maternal chorioamnionitis in the majority of cases. Fetal biophysical assessment holds promise as a method to assess fetal well-being and predict the development of infectious complications. The frequent use of fetal biophysical profiles in patients with PROM helps to distinguish healthy fetuses from those infected or at high risk of infection. This distinction enables the physician to intervene appropriately and in a timely manner. The recognition of the healthy fetus allows for safe prolongation of pregnancy. This article reviews the published experience using antepartum fetal biophysical monitoring in patients with PROM.