A ratiometric fluorescence platform based on boric-acid-functional Eu-MOF for sensitive detection of H2O2 and glucose.

A Eu-metal organic framework (Eu-MOF) probe with dual-emission was reported for the ratiometric fluorescence detection of H2O2 and glucose. Because of the special nucleophilic reaction between boric group and H2O2, Eu3+ and 5-boronobenzene-1,3-dicarboxylic acid (BBDC) were selected to synthesize the functional MOF probe via a simple one-pot solvothermal method. The Eu-MOF shows dual-emission at 370 and 623 nm with the single excitation at 270 nm due to the energy transfer efficiency change for antenna effect procedure. After addition of H2O2, the red emission of Eu-MOF weakened and the blue emission enhances immediately under 270 nm irradiation, so the ratiometric fluorescence detection is established. Moreover, the obvious color change for visual measuring of H2O2 and glucose is illustrated to reveal the merit of Eu-MOF probe. The proposed method was demonstrated to be highly sensitive and selective for H2O2 and glucose, with the low detection limits of 0.0335 and 0.0643 μM, respectively. The established boric-acid-functional Eu-MOF sensing platform was proved as the powerful probe for H2O2 and the metabolites involved in H2O2-generating reaction.