Miniaturized thermal purge-and-trap device combined with self-calibration colorimetric/SERS dual-model optical sensors for highly rapid and selective detection of sulfur dioxide in wine.

Herein, the miniaturized thermal purge-and-trap (MTPT) device combined with self-calibration colorimetric/surface-enhanced Raman spectroscopy (SERS) dual-model optical sensors were designed for effective analysis of sulfur dioxide (SO2) in wine. The SO2 can be rapidly separated from wine and enriched by MTPT device, ensuring colorimetric/SERS dual-model optical sensing based on Karl Fischer reaction. The high separation efficiency of miniaturized MTPT device combined with self-calibration of dual-model optical sensors significantly alleviate matrix interference and improve the detection accuracy. The satisfactory linear range of 0.1-200.0 mg/L and 0.1-500.0 mg/L with limit of detection of 0.03 mg/L can be obtained. Finally, the MTPT-colorimetric/SERS method was applied to determine the content of SO2 in different kinds of wine to verify the practicality. These results provide an ideal strategy in construction of MTPT device combined with self-calibration dual-model optical sensors for quantification of gaseous hazards in complex food samples with high rapidity, anti-interference and accuracy.