Ovary hyperstimulation syndrome accompanying molar pregnancy: case report and review of the literature.

PURPOSE: To describe a naturally conceived woman with ovary hyperstimulation syndrome (OHSS) accompanying molar pregnancy and review the literature on this condition.

METHODS

We report a 31-year-old 2 parous naturally conceived woman with OHSS accompanying partial molar pregnancy. Dilatation and evacuation (D&E) were performed at 10 weeks of gestation. The signs and symptoms of OHSS were the severest on day 8 after D&E, when hCG had already decreased. This case is reported in detail. We also review the literature.

RESULTS

A literature search yielded seven cases of this condition. Any type of molar pregnancy, i.e., complete, partial, or invasive, can accompany OHSS. The initial manifestation of OHSS occurred at a median of the 12th week of gestation (range 7-16), which may be later compared with OHSS caused by ovulation induction. In all cases, OHSS aggravated after D&E.

CONCLUSIONS

We must be aware that OHSS can occur during molar pregnancy, and can be exacerbated after D&E.