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DOI 10.1038/s41372-026-02560-w

Медицинская библиотека · Journal of perinatology : official journal of the California Perinatal Association · 2026

Down syndrome birth rate post Dobbs decision: has it changed?

Santoro Stephanie L, Alvarado Chance, Tseng Stephanie Y, Conroy Sara, Kistler Isaac, Hart Stephen A, Fichtner Samantha, Cua Clifford L

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Аннотация

OBJECTIVE

In 2022, the U.S. Supreme Court decision on Dobbs v. Jackson Women's Health Organization changed abortion access. We evaluated birth rates of Down syndrome (DS) before and after the Dobbs decision hypothesizing similarity to cyanotic congenital heart disease.

STUDY

DESIGN

Retrospective cohort study of live births utilizing 2016 - 2025 CDC birth certificate registry data stratified by DS and by state abortion access categories (restrictive and protective) based on the Guttmacher Institute. Incidence of DS and the difference in incidence between state cohorts were modeled and compared between pre- and post-Dobbs periods using segmented linear regression.

RESULTS

Incidence of DS live births remained stable in restrictive and protective states pre- and post-Dobbs. Segmented regression models revealed no significant changes in monthly incidence in the post-Dobbs era nationally compared to pre-Dobbs.

CONCLUSIONS

Mean monthly incidence of DS in live-born infants using CDC birth certificate data did not increase after the Dobbs decision.

Для цитирования: Santoro Stephanie L, Alvarado Chance, Tseng Stephanie Y, Conroy Sara, Kistler Isaac, Hart Stephen A, Fichtner Samantha, Cua Clifford L. Down syndrome birth rate post Dobbs decision: has it changed?. Journal of perinatology : official journal of the California Perinatal Association. 2026. DOI: 10.1038/s41372-026-02560-w.
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