Thurston syndrome: report of a new case.

Thurston syndrome (oro-facial-digital syndrome type V) is an autosomal recessive condition characterized by median cleft of the upper lip, postaxial polydactyly of hands and feet, and oral manifestations. According to earlier reports, the syndrome is predominantly seen in subjects of Indian descent. We report a cast of Thurston syndrome in a 13-year-old south Indian boy who presented with oral features, incomplete median cleft of upper lip, and polydactyly of both hands and left foot. A precise clinical differentiation must be made since considerable overlap of the features of the various other forms could give rise to difficulties in diagnosing the condition.