European journal of obstetrics, gynecology, and reproductive biology · 2001
The concentrations of osteocalcin and degradation products of type I collagen in pregnant women with pre-eclampsia.
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Gorzelak M, Darmochwal-Kolarz D, Jablonski M, Rolinski J, Leszczynska-Gorzelak B, Modrzewski K, Oleszczuk J
Аннотация
OBJECTIVES: To investigate the concentrations of osteocalcin and collagen type I C-terminal telopeptides in pregnant women with pre-eclampsia.
STUDY DESIGN: 26 patients with severe pre-eclampsia and 24 healthy pregnant women were included in the study. Serum concentrations of osteocalcin and C-telopeptides--degradation products of type I collagen were determined using the ELISA method. Statistical analysis was performed using Mann-Whitney U-test.
RESULTS: In pre-eclamptic patients, the concentrations of osteocalcin and degradation products of collagen type I were significantly higher (P<0.005) when compared to healthy pregnant women.
CONCLUSION: These results could suggest that there are alterations in bone metabolism in pregnant women with pre-eclampsia.
STUDY DESIGN: 26 patients with severe pre-eclampsia and 24 healthy pregnant women were included in the study. Serum concentrations of osteocalcin and C-telopeptides--degradation products of type I collagen were determined using the ELISA method. Statistical analysis was performed using Mann-Whitney U-test.
RESULTS: In pre-eclamptic patients, the concentrations of osteocalcin and degradation products of collagen type I were significantly higher (P<0.005) when compared to healthy pregnant women.
CONCLUSION: These results could suggest that there are alterations in bone metabolism in pregnant women with pre-eclampsia.