[Recurrent tubal pregnancy after a intra-tubal injection of methotrexate. Analysis of an case report with a histological tubal study].

A second tubal pregnancy occurred in the same tube as the first one which had been treated with methotrexate injection. The hysterosalpingogram performed 3 months after the methotrexate injection was normal. The recurrent tubal pregnancy was treated by laparoscopic salpingectomy. The pathology report confirmed non-ruptured tubal pregnancy. No damage to the tube could be imputed to the methotrexate injection. This observation confirms that methotrexate has no deleterious effect on tubal epithelium but also emphasizes that recurrent ectopic pregnancy can occur despite a patent tube.