[Advances of clinical diagnosis of osteodystrophy complicated by chronic renal failure].

Renal osteodystrophy complicated chronic renal failure presents many clinical problems because of multiple pathogenetic factors, non specific clinical symptoms as well as not precisely enough methods evaluating progress and treatment efficacy of this complications. The paper is a review of such approved markers of bone turnover as intact PTH, bone specific alkaline phosphatase, calcium and phosphorus, bone biopsy and DEXA, as well as new bone turnover markers. Special references are referred to procollagen type I carboxyterminal (PICP) and aminoterminal (PINP), osteocalcin as new markers of bone formation process and to tartare resistant acid phosphatase pyridynoline, deoxypyridynoline and carboxyterminal telopeptide type I collagen (ICTP) as new markers of bone resorption process.